The importance of testing anti-dsDNA, anti-nucleosome and anti-C1q antibodies in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by multisystem clinical presentation and serologic findings of various antibodies.
- Anti-dsDNA and anti-nucleosome have high specificity and positive predictive value for Systemic lupus erythematosus (SLE) diagnosis
- Anti-nucleosome and anti-C1q antibodies show an association with SLE and lupus nephritis activity, suggesting their potential usefulness in making predictions about lupus nephritis and assessment of disease activity
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